Liverpool travel to Goodison Park for the final time in Premier League history. Liverpool's overall league record over their local rivals is impressive but they have found it tougher of late.
This year's instalment has high ramifications with the runaway Reds keen to keep their lead at the summit.
Everton 2-0 Liverpool - Premier League - 24th April 2024
A defining blue victory last season as Everton put all fear of relegation behind them and officially took Liverpool out of the title race.
Young Jarrad Branthwaite slid home for his most memorable moment in his fledgling Toffee career to date before Dominic Calvert-Lewin bullied the Liverpool defensive from a corner to make it two-nil before the hour.
It was their first win at home against Liverpool since the same score line in 2010, where a certain Mikel Arteta was on the scoresheet.
Liverpool 2-0 Everton - Premier League - 21st October 2023
Liverpool won by the same margin in the first fixture last season as Mohamed Salah gunned down 10 man Everton late on.
Ashley Young was sent off for two moments of madness in the first half but it will still take until the 77th minute for Liverpool to make the pressure count.
Michael Keane stopped a cross with his arm and Salah stepped up to slam the pressure penalty home. Liverpool pressed on but wouldn't seal all three points until the final minute of added time.
Darwin Nunez left a few for dead before finding Salah to seal the derby win and keep Liverpool's early momentum going.
Liverpool 2-0 Everton - Premier League - 13th February 2023
Another win by the same score line as Liverpool overcame a patch winter period with a big Anfield win in the derby.
The opening period was largely controlled by Liverpool and they did take a lead into the break. A clinical home counter saw Nunez sent a ball in and Pickford lost his bearings before Salah poked home in the opener.
Liverpool may have feared a Toffee resurgence but they sealed all three points early in the second half.
Another swift break eventually led to a ball to the back post and Cody Gakpo lashed home a second.
Everton 0-0 Liverpool - Premier League - 3rd September 2022
A very forgettable derby at Goodison and a rare deadlock between the two sides. Both goalkeepers were on top and big chances were missed.
Everton did put the ball in the net late in the second half but Conor Coady's celebrations were halted by a long VAR decision.
Liverpool's main chance came in the very final moment. Usually clinical Mo Salah put a rebound wide and the whistle brought an end to a largely forgettable game.
Liverpool 2-0 Everton - Premier League - 24th April 2022
The fourth 2-0 score line in the last five meetings between the two! Liverpool would once again be frustrated for an hour before sealing the win late on.
A rare Liverpool goal for Scottish defender Andy Robertson finally broke the deadlock before cult hero Divock Origi slotted home on the break.
It kept Liverpool hot on the heels of leaders Manchester City but despite an extremely impressive 92 points, Liverpool would ultimately have to settle for second place.