Liverpool will look to end a mini-two match Premier League "slump" that has seen them held to consecutive draws with Newcastle and Fulham.
With those results, coupled with a surging Chelsea side, the Reds could very well be 2nd when they kickoff their meeting with Tottenham on Sunday. Granted, they would have a game in hand, but the narrative has certainly flipped.
Arne Slot will be looking for a response from his side as this fixture usually puts on a great show no matter the standing of either club.
There are some key players still out like Ibrahima Konate and Conor Bradley, but the likes of Mohamed Salah and Virgil van Dijk were rested midweek and should be refreshed.
Let's see how Liverpool could lineup for Sunday's matinee with Spurs.
Goalkeeper: Alisson Becker
Defenders: Trent Alexander-Arnold, Joe Gomez, Virgil van Dijk, Andy Robertson
Midfielders: Alexis Mac Allister, Ryan Gravenberch, Curtis Jones
Forwards: Mohamed Salah, Darwin Nunez, Luis Diaz
Probable Subs: Harvey Elliott, Cody Gakpo, Federico Chiesa, Dominik Szoboszlai, Diogo Jota
Alisson makes his return to goal after Caoimhin Kelleher handled the cup duties during the week and the Brazilian will need to be on his game to shutdown the likes of Son Hueng-Min.
The defense sees four club stalwarts as I expect Slot will want as much experience for a match of this magnitude as he can get on the pitch. Quansah was fine midweek, but doesn't appear fully ready for this pressure again at the moment.
In the midfield, Mac Allister was removed after around 60 minutes on Wednesday and he will be wanting to make amends for a largely invisible performance in the EFL Cup win.
Gravenberch, fully rested, is an obvious start for Liverpool while Curtis Jones barely edges out Dominik Szoboszlai for the start. These two are so interchangeable that either one starting is not a shock whatsoever.
As we move up top, Salah returns to the XI where he will look to maintain his sensational form in all competitions this season. Darwin gets the nod over Jota, but just by a pinch. Like Jones and Szobo, these two are neck-and-neck for the center forward role.
Finally, Luis Diaz gets the start out wide at the expense of Gakpo who looked good once again versus Southampton in the Cup quarterfinal.
Slot nailing the right mixture for this match is going to be hugely important as surely more than one goal is going to be required to secure maximum points and the Reds cannot come out offbeat.